Hindi English Translation || Editorial || Nose dose: On nasal COVID-19 vaccine

Nose dose: On nasal COVID-19 vaccine

The nasal vaccine against COVID-19 should help in quicker coverage of the population

The history of the pandemic (वैश्विक महामारी) has been punctuated (बीच में रोकना, टोकना) periodically (समय-समय पर, आवधिक) by incremental developments in science and medicine. Funding, industry, and research were ploughed (To turn the soil using a plow) into laboratories with the hope that their petri dishes would yield solutions to save lives and retard (To make slow) the march of the virus. While many vaccines have provided that assurance of life, prevented hospitalisation and also reduced the severity (तीव्रता, कठोरता, क्रूरता) of disease, it is only a nasal vaccine that carries within it the promise of preventing further transmission (संचारण, हस्तांतरण, सौंपना) by countering it at the site of viral entry into the body. In that sense, the announcement that a nasal vaccine had been given emergency use authorisation for use as primary immunisation to the 18-plus age group is welcome. A nasal vaccine, if effective, is probably the most advanced tool to handle COVID-19 as of now, and by virtue of being a spritz (To disperse a spray) in the nose or mouth, will be preferable to painful jabs (प्रहार करना, मार लगाना), particularly with children or adults with trypanophobia that might have come in the way of their getting the vaccines. While in theory the nasal vaccine ensures that the virus is stopped from binding with host cells at the very point of entry into the human body, there is very little evidence (सबूत) of that working in a COVID-19 scenario among humans. While an influenza nasal vaccine has reportedly worked, three other nasal vaccines have been approved for use elsewhere in the world, but very little data is available from that. In the trials conducted by the Bharat Biotech for the nasal vaccine, developed in association with the University of Washington, “the reactogenic events and adverse events that were documented during the trial were highly comparable to the published data from other COVID-19 vaccines”. The company reportedly conducted a phase 3 trial with about 3,100 unvaccinated people who received two doses of the nasal vaccine, and a booster (Someone or something that boosts and acts as support) trial with about 875 people who received a single dose of the nasal vaccine as a heterogeneous (विषमलैंगिक, विषमांग) booster. The company has also promised that it would publish the data from the trials soon in the public realm (क्षेत्र, राज).

While the fall in cases has allowed the world to take its foot off the pedal, efforts against the disease will have to be pursued (पीछा करना, लक्ष्य रखना). But this drop in numbers does afford a certain pause in pace: the results of the trials and data must now be allowed to enter the public realm even as emergency use authorisation is being processed for use of drugs or vaccines in the community. The Government too must factor this in its agenda, emphasising the promotion of transparency, now and in the future, even as it ensures continuing commitment of various departments involved in battling all aspects of the virus. In addition, delivering the vaccines to the general public and covering those untouched by the primary two doses, and the boosters, should remain high on the agenda.

Courtesy: The Hindu

Important Word List With Meaning

1.Pandemic (Noun)

Hindi Meaning - वैश्विक महामारी
English Meaning - A Disease occurring over a wide geographic area.

2.Punctuate (Verb)

Hindi Meaning - बीच में रोकना, टोकना
English Meaning - To divide something with punctuation marks in order to make meaning clear.

3.Periodically (Adverb)

Hindi Meaning - समय-समय पर, आवधिक
English Meaning - At regular intervals of time.

4.Severity (Noun)

Hindi Meaning - तीव्रता, कठोरता, क्रूरता
English Meaning - The condition of being very bad.

5.Transmission (Noun)

Hindi Meaning - संचारण, हस्तांतरण, सौंपना
English Meaning - The process of transmitting.

6.Jab (Verb)

Hindi Meaning - प्रहार करना, मार लगाना
English Meaning - To poke with a sharp blow.

7.Evidence (Noun)

Hindi Meaning - सबूत
English Meaning - Something that tends to prove or disprove something.

8.Heterogenous (Verb)

Hindi Meaning - विषमलैंगिक, विषमांग
English Meaning - Having its source outside the organism.

9.Realm (Noun)

Hindi Meaning - क्षेत्र, राज
English Meaning - A primary marine division of the earth’s surface.

10.Pursue (Verb)

Hindi Meaning - पीछा करना, लक्ष्य रखना
English Meaning - Follow (someone or something) in order to catch or attack them.

11.Plough (Verb)

English Meaning - To turn the soil using a plow.

12.Retard (Verb)

English Meaning - To make slow.

13.Spritz (Verb)

English Meaning - To disperse a spray.

14.Booster (Noun)

English Meaning - Someone or something that boosts and acts as support.