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Cell Cycle and Cell Division Test - 10

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Cell Cycle and Cell Division Test - 10
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  • Question 1
    1 / -0
    When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?
    Solution
    When the DNA replication in the S-phase is stalled, the DNA replication and synthesis is not complete. This causes the activation of the G$$_2$$/M checkpoint which does not allow the cell to enter the G$$_2$$ and the M phase till the replication is complete.
    So, the correct answer is $$G_2$$/M.
  • Question 2
    1 / -0
    Identify the correct statement with regard to $$G_1$$ phase (Gap 1) of interphase.
    Solution
    The $$G_1$$ phase of interphase includes synthesis of various proteins, duplication of organelles, synthesis of various enzymes etc as a preparation for the synthesis phase and cell division. Therefore, it is metabolically very active but DNA replication does not take place in this phase, it occurs in the S phase of interphase.
    So, the correct answer is 'Cell is metabolically active, grows but does not replicate its DNA.'
  • Question 3
    1 / -0
    Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
    Solution
    Anaphase promoting complex helps in the transition of the chromosome from metaphase to anaphase. The APC attaches to the chromosomes aligned at the equator during metaphase and allows the segregation of the chromatids.
    So, the correct answer is option D.

  • Question 4
    1 / -0
    Primary source of allelic variation is
  • Question 5
    1 / -0
    The G$$_{2}$$ phase of the cell cycle is signified by the synthesis of 
    Solution
    The G$$_2$$ phase is the third phase of the cell cycle; the first two being the G$$_1$$ phase and the S phase. In the S phase, the DNA has been replicated and now in G$$_2$$ phase, the cell grows and prepares itself for mitosis. To do so, it requires proteins (for example, for spindle assembly and dis-assembly). Hence, this phase is marked by protein synthesis and rapid cell growth. As it involves protein synthesis, both mRNA (required to translate into protein) and rRNA ( an essential component for protein synthesis) will be synthesized.
    So, the correct answer is option C.
  • Question 6
    1 / -0
    Which of the following is not a characteristic of meiosis?
    Solution
    DNA replication occurs once but meiosis has two M-phases each with its own karyokinesis and cytokinesis. As a result chromosome number is halved. The transition period between M-phase I (meiosis I) and M-phase II (meiosis II) is short and without DNA replication. It is called interkinesis.
    So, the correct answer is option A.
  • Question 7
    1 / -0
     Which phenomenon takes place at G$$_{1}$$ stage?
    Solution
    The first growth phase or G$$_1$$phase is the longest phase of cell cycle. There is a synthesis of biochemicals like RNA, proteins, enzymes for DNA synthesis, amino acids for histone formation, nucleotides and ATP.
    So, the correct answer is option B.
  • Question 8
    1 / -0
    In which of the following stages, chromosomes are attached on equatorial plane?
  • Question 9
    1 / -0
    Crossing over is advantageous because it brings about
    Solution
    Meiosis is the type of cell division in which homologous chromosomes separate after exchange of fragments. As a result, of meiosis four haploid cells are produced which are all genetically different from each other. This is due to the process of crossing over or exchange of segments between homologous chromosomes.
  • Question 10
    1 / -0
    Diploid cells have
    Solution
    Diploid cells have two sets of chromosomes one inherited from a female parent and one inherited from a male parent. This chromosomal constitution is designated 2n, where n denotes basic haploid chromosome set.
    So, the correct answer is option D.
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