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Chemical Coordination and Integration Test 56

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Chemical Coordination and Integration Test 56
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  • Question 1
    1 / -0
    Which one of the following flows directly into the blood from the site of its production to act on an organ away from it?
    Solution
    Renin is often improperly referred to as a hormone, although it has no peripheral receptors and rather has an enzymatic activity with which it hydrolyzes angiotensinogen to angiotensin I. The renin enzyme circulates in the blood stream and breaks down (hydrolyzes) angiotensinogen, secreted from the liver into the peptide angiotensin I.
  • Question 2
    1 / -0
    Parathormone influences calcium absorption in the small intestine by regulating the metabolism of
    Solution
    Vitamin D increases blood concentrations of calcium. It is generated through the activity of parathyroid hormone within the kidney. The most important effect of vitamin D is to facilitate absorption of calcium from the small intestine. Along with thyroid hormone, vitamin D also enhances fluxes of calcium out of bone.
  • Question 3
    1 / -0
    Which of the following is an accumulation and release center of neurohormones?
    Solution
    • The posterior pituitary or neurohypophysis is a structure under direct regulation of the hypothalamus. 
    • The nuclei of the hypothalamus accumulate vasopressin and oxytocin in this neurohypophysis which serves as the release centre of these neurohormones.

    So, the correct answer is 'Posterior Pituitary lobe'.
  • Question 4
    1 / -0
    Cholesterol is necessary for the synthesis of
    Solution
    One of cholesterol's many functions in the body is to act as a precursor to vitamin D. Since cholesterol is a precursor to vitamin D, inhibiting the synthesis of cholesterol will also inhibit the synthesis of vitamin D, which helps in calcium metabolism and bone health. Cholesterol is also needed for the synthesis of various hormones, including the sex hormones. 
  • Question 5
    1 / -0
    Which hormone has the anti-insulin effect?
    Solution
    Under stressful conditions, cortisol provides the body with glucose from protein stores via gluconeogenesis in the liver. This energy can help an individual fight or flee. Elevated cortisol over the long term consistently produces glucose, leading to increased blood sugar levels.
  • Question 6
    1 / -0
    Which one of the following is not a second messenger in hormone action?
    Solution
    Second messengers are intracellular signalling molecules, released by the cell to trigger physiological changes, such as proliferation, differentiation, migration, survival, and apoptosis. Secondary messengers are one of the initiating components of intracellular signal transduction. Examples of second messenger molecules include cyclic AMP, cyclic GMP, inositol triphosphate, diacylglycerol, and calcium. 
  • Question 7
    1 / -0
    Which among the following lacks peptides, amines, and sulphur?
    Solution
    The natural steroid hormones are synthesized from cholesterol in the gonads and adrenal glands. These forms of hormones are lipids. They can pass through the cell membrane as they are fat soluble, and then bind to steroid hormone receptors. Pituitary, thyroid and adrenal gland secrete hormones, some of which are peptides and some are derived from amino acids. 
  • Question 8
    1 / -0
    Which one of the following four secretions is correctly matched with its source, target, and nature of action?

    Secretion
    Source
    Target
    Action
    (a)
    Gastrin
    Stomach
    lining
    Oxyntic cell
    Production of
    HCI
    (b)
    Inhibin
    Sertoli cells
    Hypothalamus
    Inhibition of
    secretion of
    gonadotropin
    releasing
    hormone
    (c)
    Enterokinase
    Duodenum
    Gall bladder
    Release of
    bile juice
    (d)
    Atrial
    Natriuretic
    Factor (ANF)
    Walls of the 
    atria
    Juxta-glomerular
    apparatus
    (JGA)
    Inhibition of
    release of
    renal renin
    Solution
    Atrial Natriuretic Factor (ANF) is a hormone produced by the right atrium of the heart. ANF regulates kidney function by opposing the regulation by the Renin-Angiotensinogen Aldosterone system (RAR's). It acts on the JGA to inhibit the release of renin. ANF stimulates the excretion of sodium and water by the kidneys and helps lower blood pressure.
    Thus, the correct answer is option D. 
  • Question 9
    1 / -0
    Sumit went to a funfair with his friends Amit and Rohit. Rohit and Amit were scared to sit on a merry-go-round and preferred to stroll around. Sumit was very excited when he came down the merry-go-round. How will this change the pH of his blood?
    Solution
    Sumit went for the merry-go-round and was very excited when he came down. This is due to the release of the hormone adrenaline which is the emergency hormone. The hormone causes the person to be excited in the conditions like fright. There will be no change in the pH of the blood and the hormone does not cause any effect on the pH.
    Thus, the correct answer is option C. 
  • Question 10
    1 / -0
    Insulin is made of
    Solution
    A. CORRECT ANSWER- D
    B. EXPLANATION FOR THE CORRECT ANSWER

    • Insulin is a peptide hormone secreted in an inactive form by the beta cells in the pancreatic Islet of Langerhans.
    • It is composed of two peptide chains referred to as the A chain and the B chain. 
    • A and B chains are linked together by two disulphide bonds and an additional disulphide bond is formed within the A chain.
    • In most species, the A chain consists of 21 amino acids and the B chain is composed of 30 amino acids.
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