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Molecular Basis of Inheritance Test - 23

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Molecular Basis of Inheritance Test - 23
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  • Question 1
    1 / -0

    In some viruses, DNA is synthesised by using RNA as template. Such a DNA is called:

    Solution

    Complementary DNA (cDNA) is double-stranded DNA synthesized from a messenger RNA (mRNA) template in a reaction catalysed by the enzyme reverse transcriptase.

  • Question 2
    1 / -0

    If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is :

    5' - A T G A A T G - 3',

    the sequence of bases in its RNA transcript would be;

    Solution

    5' - A T G A A T G - 3' (coding strand)

    5'- T A C T T A C - 3' (complementary)

    5' -A U G A A U G - 3' (RNA)

  • Question 3
    1 / -0

    The RNA polymerase holoenzyme transcribes:

    Solution

    Transcription involves three separate process : initiation, elongation and termination. Initiation begins when the RNA polymerase binds to the promoter which serves only as a target site for binding of the RNA polymerase and is not transcribed. Each gene contains a specic promoter region for guiding the beginning of transcription. This is followed by region of gene (structural gene) that is transcribed and ends with a terminator that stops transcription.

  • Question 4
    1 / -0

    If the base sequence of a codon in mRNA is 5'-AUG-3', the sequence of tRNA pairing with it must be:

    Solution

    The sequence of tRNA pairing with it must be 5' - CAU - 3'

  • Question 5
    1 / -0

    The amino acid attaches to the tRNA at its:

    Solution

    AA-binding site (amino acid binding site) lies at the 3'end opposite the anticodon and has CCA-OH group. It is the site where aminacid attaches to the tRNA.

  • Question 6
    1 / -0

    To initiate translation, the mRNA first binds to:

    Solution

    The ribosome consists of structural RNAs and about 80 different proteins, in its inactive state, it exist as two subunits, a large subunit and a small subunit. When the smaller subunit encounters the mRNA, the process of translation of the mRNA to protein begins.

  • Question 7
    1 / -0

    In E.coli, the lac operon gets switched on when:

    Solution

    In case of lactose presence

    (i)  Lactose acts as an inducer which binds to the repressor and forms an inactive repressor.

    (ii)  The repressor fails to bind to the operator region.

    (iii)  The RNA polymerase binds to the operator and transcript lac mRNA.

    (iv)  lac mRNA is polycistronic, i.e., produces all three enzymes, -galactosidase, permeaseand transacetylase.

    (v)  The lac operon is switched on.

    In case of lactose absence

    (i)  When lactose is absent, i gene egulates and produces repressor mRNA which translate repression.

    (ii) The repressor protein binds to the operator region of the operon and as a resultprevents RNA polymerase to bind to the operon.

    (iii) The operon is switched off. 

  • Question 8
    1 / -0

    Viviparity is considered to be more evolved because: 

    Solution

    The young ones are protected inside the mother's body and are looked after they are born leading to more chances of survival

  • Question 9
    1 / -0

    For the MN-blood group system, the frequencies of M and N alleles are 0.7 and 0.3, respectively. The expected frequency of MN-blood group bearing organisms is likely to be 

    Solution

    The expected frequency of MN-blood group bearing organisms is likely to be 42%.

  • Question 10
    1 / -0

    Who supported Griffith effect by molecular explanation ?

    Solution

    Griffith's experiment was an experiment done in 1928 by Frederick Griffith. Supported by Avery, McLeod and McCarty and by Hershey and Chase.

  • Question 11
    1 / -0

    Name the conjugated protein used as genetic material in living cells 

    Solution

    Nucleoprotein used as genetic material in living cells.

  • Question 12
    1 / -0

    Which one of the following does not follow the central dogma of molecular biology ? 

    Solution

    HIV does not follow the central dogma of molecular biology

  • Question 13
    1 / -0

    Polysome is formed by 

    Solution

    Several ribosomes attached to a single m RNA

  • Question 14
    1 / -0

    Anti parallel strands of a DNA molecule means that 

    Solution

    The phosphate groups at the start of two DNA strands are is opposite position (Pole)

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