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Molecular Basis...

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  • Question 1
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    Select the correct option that correctly fill the blanks i - iv
    I. Less than (i) of genome represents structural genes that code for proteins.
    II. Chemical substance that binds with repressor and convert it into a non-DNA binding State is (ii).
    III. In prokaryotes, during replication RNA primer is removed by (iii) whereas in eukaryotes it is removed by (iv).

  • Question 2
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    Match column I with column II and select the correct option from the-given codes.

    Column I
    (Codons)
    Column II
    (Translated amino acid)
    A.UUU(i)Serine
    B.GGG(ii)Methionine
    C.UCU(iii)Phenylalanine
    D.CCC(iv)Glycine
    E.AUG(v)Proline

  • Question 3
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    The promoter site and the terminator site for transcription are located at

  • Question 4
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    Transcription unit

  • Question 5
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    Which of the following statements regarding human genome is incorrect?

  • Question 6
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    Choose the correct answer from the alternatives given :
    A DNA template plus primer with the structure
    3 P - TG C GAATTAG C GACAT - P5
    5 P - ATCGGTACGACGCTTAAC OH 3
    (where P = a phosphate group) is placed in an in vitro DNA synthesis system containing $$Mg^{2+}$$, an excess of the four deoxyribonucleoside triphosphates, etc. and a mutant form of E. Coli DNA polymerase I that lacks 5 $$\rightarrow$$ 3 exonuclease activity. The 5 $$\rightarrow$$ 3 polymerase and. 3 $$\rightarrow$$ 5 exonuclease activities of this aberrant enzyme are identical to those of normal E. Coli DNA polymerase I. It simply has no 5 $$\rightarrow$$ 3 exonuclease activity. What will be the structure of the final product?

  • Question 7
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    Choose the correct answer from the alternatives given :
    If Meselson and Stahls experiment is continued for four generations in bacteria, the ratio of $$N^{15}$$- $$N^{15}$$, $$N^{14}$$ - $$N^{15}$$, $$N^{14}$$ - $$N^{14}$$  containing DNA in the fourth generation would be

  • Question 8
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    DNA is a polymer of nucleotides which are linked to each other by 3-5 phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?

  • Question 9
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    Which of the following statements are correct?
    (i) RNA polymerase I transcribes rRNAs.
    (ii) RNA polymerase II transcibes snRNAs.
    (iii) RNA polymerase III transcibes hnRNA,
    (iv) RNA polymerase II transcribes hnRNA.

  • Question 10
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    Choose the correct answer from the alternatives given :
    Discontinuous synthesis of DNA occurs in one strand, because

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