Molecular Basis of Inheritance Test

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Molecular Basis of Inheritance Test - 4

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Weekly Quiz Competition

Question 1
1 / -0

In DNA, two nucleotides are linked by

A
hydrogen bonds

B
peptide bonds

C
disulphide bonds

D
phosphate diester bonds

Solution

When nucleotides are incorporated into DNA, adjacent nucleotides are linked by a phosphodiester bond: a covalent bond is formed between the 5' phosphate group of one nucleotide and the 3'-OH group of another. In this manner, each strand of DNA has a backbone of phosphate-sugar-phosphate-sugar-phosphate.
Question 2
1 / -0

DNA generally acts as a template for the synthesis of

A
protein only

B
DNA only

C
RNA only

D
RNA and DNA both

Solution

DNA generally acts as a template for the synthesis of DNA during replication and RNA during transcription. DNA does not act as a template for the synthesis of protein.
Question 3
1 / -0

Haploid chromosome number is 10. What will be its monosomy?

A
18

B
19

C
21

D
17

Solution

Monosomy means 2n - 1, i.e. (2 × 10) - 1 = 20 - 1 = 19.
Question 4
1 / -0

The following question has four choices out of which ONLY ONE is correct.

The genetic codes representing amino acid valine are

A
GGU,GGC,GGA,GGG

B
CUU,CUC,CUA,CUG

C
GCU,GCC,GCA,GCG

D
GUU,GUC,GUA,GUG

Solution

GUU,GUC,GUA,GUG represents valine.
Question 5
1 / -0

Teminism is a phenomenon which refers to

A
mutual activity of operator and promoter genes

B
central biological dogma

C
reverse transcription

D
transduction in bacteria

Solution

Reverse transcription is the formation of DNA from RNA by enzyme reverse transcriptase. This phenomenon was discovered by Temin and Baltimore and thus, is known as 'Teminism'.
Question 6
1 / -0

Which enzyme catalyses the synthesis of DNA from RNA?

A
Restriction enzyme

B
DNA polymerase

C
RNA polymerase

D
Reverse transcriptase

Solution

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription.
Question 7
1 / -0

Select the wrong statements about genes.
A. Genes are arranged in a linear fashion on the chromosomes.
B. Genes cannot be replicated and inherited to the progeny.
C. Genes do not carry all the necessary information for the progeny.
D. Genes are susceptible to mutations.
E. All dominant genes give positive changes in phenotypes.

A
A, B and C

B
B, C and E

C
C, D and E

D
A, B and E

Solution

B, C and E statements are not true of genes. Genes can be replicated and inherited to the progeny. This has been proved by linkage and crossing over of genes.
Genes carry all the necessary information for the progeny. All dominant genes need not be giving positive changes in phenotypes.
Question 8
1 / -0

Proof reading enzyme during the synthesis of new bacterial DNA from template DNA is

A
helicase

B
primase

C
DNA polymerase

D
ligase

Solution

The term proofreading is used in genetics to refer to the error-correcting processes. In bacteria, all three DNA polymerases (I, II and III) have the ability to proofread, using 3' → 5' exonuclease activity. When an incorrect base pair is recognized, DNA polymerase reverses its direction by one base pair of DNA and excises the mismatched base. Following base excision, the polymerase can re-insert the correct base and replication can continue.
In eukaryotes only the polymerases that deal with the elongation (delta and epsilon) have proofreading ability (3' 5' exonuclease activity).
Question 9
1 / -0

The number of nucleotides in the gene which code for dystrophin protein is

A
3000 base pairs

B
1 million base pairs

C
2.4 million base pairs

D
1.2 million base pairs

Solution

The DMD gene, encoding the dystrophin protein, is one of the longest human genes known. The number of nucleotides in the gene are 2.4 million base pairs.
Question 10
1 / -0

In sickle cell anaemia due to point mutation, the sixth amino acid, glutamic acid in beta chain of haemoglobin is replaced by

A
alanine

B
tyrosine

C
valine

D
serine

Solution

In sickle cell anaemia due to point mutation, the sixth amino acid, glutamic acid in beta chain of haemoglobin is replaced by valine. Sickle cell anaemia results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells.
Sickle cell disease occurs when a person inherits two abnormal copies of the haemoglobin gene, one from each parent.

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Re-Attempt Weekly Quiz Competition

Molecular Basis of Inheritance Test - 4

Result

Molecular Basis of Inheritance Test - 4

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SHARING IS CARING

Question 1

hydrogen bonds

peptide bonds

disulphide bonds

phosphate diester bonds

Solution

Question 2

protein only

DNA only

RNA only

RNA and DNA both

Solution

Question 3

18

19

21

17

Solution

Question 4

GGU,GGC,GGA,GGG

CUU,CUC,CUA,CUG

GCU,GCC,GCA,GCG

GUU,GUC,GUA,GUG

Solution

Question 5

mutual activity of operator and promoter genes

central biological dogma

reverse transcription

transduction in bacteria

Solution

Question 6

Restriction enzyme

DNA polymerase

RNA polymerase

Reverse transcriptase

Solution

Question 7

A, B and C

B, C and E

C, D and E

A, B and E

Solution

Question 8

helicase

primase

DNA polymerase

ligase

Solution

Question 9

3000 base pairs

1 million base pairs

2.4 million base pairs

1.2 million base pairs

Solution

Question 10

alanine

tyrosine

valine

serine

Solution

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