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Molecular Basis of Inheritance Test - 34

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Molecular Basis of Inheritance Test - 34
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  • Question 1
    1 / -0
    What is the name of double helix model of Watson and Crick?
    Solution
    Watson and Crick shared the Nobel prize in 1962 for their discovery, along with Maurice Wilkins for producing crystallographic evidence for a helical structure of DNA, which is called as B-DNA.

  • Question 2
    1 / -0
    Purines possess nitrogen at which position?
    Solution
    Purines consist of a six-membered and a five-membered nitrogen containing ring, fused together. It possesses nitrogen at 1,3,7 and 9$$^{th}$$ position.
    So, the correct answer is option C.

  • Question 3
    1 / -0
    Nucleotides in the two helical strands of DNA are held together by
    Solution
    The nucleotides in the two helical strands of the DNA are held together by Hydrogen bonds. The nitrogenous bases are present in an inward direction of the strand. These nitrogenous bases of the two antiparallel strands make hydrogen bonds together and thus, two helical strands are joined.
    Thus, the correct answer is (A).
  • Question 4
    1 / -0
    DNA repair in prokaryotes in carried out by
    Solution
    DNA repair is a collection of processes, by which a cell identifies and corrects damage to the DNA molecules that encode its genome. DNA polymerase II is the major enzyme which plays an important role in DNA repair as it has 3'-5; exonuclease activity and polymerizes the nucleotide bases.
    Thus, the correct answer is option C.
  • Question 5
    1 / -0
    Who among the following did not provide experimental proof for the semiconservative model of DNA replication?
    Solution
    Watson and Crick model never gave any clue about semiconservative mode of DNA replication but they gave details about the double-helical structure of DNA. The DNA model proposed by them was termed as B - DNA.
  • Question 6
    1 / -0
    What is the width of DNA molecule?
    Solution
    The width of the double-stranded DNA (B DNA) molecule is around 2nm or 20 angstroms. 
    So, the correct answer is (B).

  • Question 7
    1 / -0
    The 3'- 5' phosphodiester linkages inside a polynucleotide chain serve to join
    Solution
    Each strand of DNA consist of number of nucleotides. The successive nucleotides of the same strand are linked by 3'-5' phosphodiester linkages i.e., 3' carbon of one sugar and 5' carbon of another sugar. This bond is strong covalent bond formed by one phosphate group and two ester groups at pentose sugars. Thus option A is the correct answer. 

  • Question 8
    1 / -0
    Okazaki fragments are linked by
    Solution
    DNA ligase is a specific type of enzyme, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
    So, the correct answer is 'ligase'

  • Question 9
    1 / -0
    During Meselson and Stahl's experiments, heavy DNA was distinguished from normal DNA by which type of centrifugation?
    Solution
    In the following procedure, centrifugation is done on a CsCl gradient, the DNA separate out at a point when density equals that of the salt solution. 
    15NH4Cl was used as a heavy isotope of ammonium chloride while,   14
    NH4Cl  was used as the light isotope of ammonium chloride & the type of centrifugation used was density gradient centrifugation in a CsCl medium.  
    So, the correct answer is "CsCl gradient".
  • Question 10
    1 / -0
    The codons causing chain termination (stop codons) are 
    Solution
    Non-sense codons are the codons which does not code for any amino acid. These are found important in terminating translation. For example, UAA, UAG and UGA.
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